In the city of San Zucchini, Dr. Putrid T. Gangreen (again voiced by John Astin), through experiments, grew ordinary tomatoes into humanized killing machines. Head tomato Zoltan overthrew the doctor, sparking the "Great Tomato War" with the human race, in which giant mutant tomatoes raged across the land. Five years after the war things were returning to normal, but federal law made it illegal to eat, own, transport or sell a tomato. There were, however, a few tomatoes that didn't turn bad. “Fuzzy Tomato” (or F.T.) changed loyalties and fled to the tomato-hating world, where he masqueraded as “the world’s ugliest dog” to survive. Another tomato outcast was Tara, who as a result of Gangreen’s experiments, looked like a sixteen-year-old human but reverted to tomato form if she came into contact with salt. (She could always be returned to human form simply by sprinkling pepper on her). The two lonely tomatoes were befriended by ten-year-old Chad Finletter, the only human who knew their secret, and together the three fought against Zoltan and Gangreen’s fiendish plots.